CMap Candidate Details
Structure:
| CMap ID: | C02299 |
| Pert ID: | BRD-K28217197 |
| Compound Name: | ganaxolone |
| Targets: | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6 |
| MoA: | GABA receptor modulator |
| SMILES: | CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119943 | BRD-K28217197 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119984 | BRD-K28217197 | A549 | 1.11 uM | 24 h | 0.31 | 1.28 | 0.62 | -0.23 | -0.78 | 0.09 |
| 120024 | BRD-K28217197 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120049 | BRD-K28217197 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.76 |
| 120100 | BRD-K28217197 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120143 | BRD-K28217197 | MCF??7.00 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.69 |
| 120182 | BRD-K28217197 | PC3 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.76 | 0.07 |
| 120214 | BRD-K28217197 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |