CMap Candidate Details
Structure:
| CMap ID: | C02301 |
| Pert ID: | BRD-K38852836 |
| Compound Name: | ganetespib |
| Targets: | HSP90AA1 |
| MoA: | HSP inhibitor |
| SMILES: | CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3n(C)ccc3c2)c(O)cc1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95546 | BRD-K38852836 | A549 | 10 uM | 6 h | -0.25 | -1.06 | 0.26 | 0.0 | 0.0 | 0.0 |
| 95681 | BRD-K38852836 | U2OS | 1.11 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121591 | BRD-K38852836 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.77 | 0.08 |
| 129580 | BRD-K38852836 | A375 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129598 | BRD-K38852836 | HELA | 0.01 uM | 24 h | -0.33 | -1.36 | 1.06 | -0.35 | -1.17 | 1.11 |
| 129628 | BRD-K38852836 | HT29 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.23 | 1.19 |
| 129658 | BRD-K38852836 | MCF??7.00 | 0.01 uM | 24 h | 0.25 | 1.02 | 0.13 | -0.37 | -1.24 | 1.31 |
| 129682 | BRD-K38852836 | PC3 | 0.01 uM | 24 h | -0.22 | -0.93 | 0.07 | -0.37 | -1.25 | 1.35 |
| 129721 | BRD-K38852836 | YAPC | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |