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CMap Candidate Details

Structure:
CMap ID: C02303
Pert ID: BRD-K64451768
Compound Name: GANT-58
Targets: GLI1
MoA: GLI antagonist
SMILES: c1cc(ccn1)-c1sc(c(c1-c1ccncc1)-c1ccncc1)-c1ccncc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8965 BRD-K64451768 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9470 BRD-K64451768 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11536 BRD-K64451768 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11804 BRD-K64451768 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12097 BRD-K64451768 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.56
12356 BRD-K64451768 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.13
12835 BRD-K64451768 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13492 BRD-K64451768 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115663 BRD-K64451768 A549 10 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
115699 BRD-K64451768 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115737 BRD-K64451768 HCC515 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115778 BRD-K64451768 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115826 BRD-K64451768 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115872 BRD-K64451768 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115908 BRD-K64451768 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).