CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02307
Pert ID:	BRD-A74980173
Compound Name:	gatifloxacin
Targets:
MoA:	bacterial DNA gyrase inhibitor
SMILES:	COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1367	BRD-A74980173	U2OS	10 uM	48 h	0.0	0.0	0.0	0.0	0.0	0.0
19219	BRD-A74980173	A549	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.12	0.93
20210	BRD-A74980173	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
20841	BRD-A74980173	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
21686	BRD-A74980173	VCAP	10 uM	6 h	0.22	0.93	0.04	0.0	0.0	0.0
91394	BRD-A74980173	HUH7	8 uM	72 h	0.34	1.42	1.1	0.0	0.0	0.0
126353	BRD-A74980173	A375	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126414	BRD-A74980173	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.32	1.14	0.87
126464	BRD-A74980173	HELA	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126546	BRD-A74980173	MDAMB231	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134386	BRD-A74980173	HA1E	0.74 uM	24 h	0.0	0.0	0.0	-0.31	-1.06	0.72
134446	BRD-A74980173	HT29	0.25 uM	24 h	0.33	1.36	0.97	0.0	0.0	0.0
134481	BRD-A74980173	HUVEC	0.03 uM	24 h	-0.29	-1.19	0.55	-0.35	-1.19	1.15
134531	BRD-A74980173	MCF10A	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134614	BRD-A74980173	PC3	0.08 uM	24 h	-0.21	-0.89	0.04	0.26	0.91	0.23
134642	BRD-A74980173	YAPC	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary