CMap Candidate Details
Structure:
| CMap ID: | C02320 |
| Pert ID: | BRD-K23228615 |
| Compound Name: | GDC-0980 |
| Targets: | FGR|MAP3K9|MTOR|PIK3CA|PIK3CB|PIK3CD|PIK3CG|SYK |
| MoA: | mTOR inhibitor; PI3K inhibitor |
| SMILES: | C[C@H](O)C(=O)N1CCN(Cc2sc3c(nc(nc3c2C)-c2cnc(N)nc2)N2CCOCC2)CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121393 | BRD-K23228615 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121426 | BRD-K23228615 | HELA | 10 uM | 24 h | 0.24 | 0.99 | 0.1 | 0.0 | 0.0 | 0.0 |
| 121450 | BRD-K23228615 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.75 | 0.07 |
| 121470 | BRD-K23228615 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.38 |
| 121540 | BRD-K23228615 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.18 | 1.14 |
| 129417 | BRD-K23228615 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129567 | BRD-K23228615 | PC3 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.46 | 15.35 |