CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02328
Pert ID:	BRD-K11129031
Compound Name:	gemfibrozil
Targets:	LPL\|PPARA\|SLCO1B1\|SLCO1B3\|SLCO2B1
MoA:	lipoprotein lipase activator
SMILES:	Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
7623	BRD-K11129031	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
8801	BRD-K11129031	VCAP	10 uM	6 h	0.0	0.0	0.0	0.17	0.62	0.0
52794	BRD-K11129031	HEPG2	2.5 uM	24 h	0.0	0.0	0.0	-0.24	-0.82	0.15
91397	BRD-K11129031	HUH7	12.5 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
96112	BRD-K11129031	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99001	BRD-K11129031	NEU	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
99128	BRD-K11129031	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
100076	BRD-K11129031	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
121165	BRD-K11129031	A375	0.125 uM	24 h	-0.26	-1.1	0.34	-0.37	-1.26	1.35
121236	BRD-K11129031	HA1E	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121328	BRD-K11129031	PC3	3.33 uM	24 h	0.37	1.56	1.48	0.0	0.0	0.0
129268	BRD-K11129031	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129315	BRD-K11129031	HT29	0.01 uM	24 h	0.2	0.85	0.01	-0.19	-0.64	0.01
129348	BRD-K11129031	MCF??7.00	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129386	BRD-K11129031	YAPC	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary