CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02329
Pert ID:	BRD-A40787240
Compound Name:	gemifloxacin
Targets:
MoA:	bacterial DNA gyrase inhibitor
SMILES:	CO\N=C1/CN(CC1CN)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
123236	BRD-A40787240	A375	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123341	BRD-A40787240	HT29	0.04 uM	24 h	0.25	1.05	0.17	0.0	0.0	0.0
123365	BRD-A40787240	MCF10A	0.125 uM	24 h	0.0	0.0	0.0	-0.3	-1.03	0.62
123494	BRD-A40787240	YAPC	0.04 uM	24 h	0.3	1.27	0.58	-0.33	-1.13	0.97
131552	BRD-A40787240	A549	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131586	BRD-A40787240	HA1E	0.08 uM	24 h	0.0	0.0	0.0	-0.24	-0.79	0.11
131627	BRD-A40787240	HEK293	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131660	BRD-A40787240	HELA	0.01 uM	24 h	0.23	0.97	0.08	0.0	0.0	0.0
131724	BRD-A40787240	HUVEC	0.03 uM	24 h	0.0	0.0	0.0	-0.37	-1.24	1.3
131778	BRD-A40787240	JURKAT	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131857	BRD-A40787240	MCF??7.00	0.03 uM	24 h	-0.24	-1.01	0.17	0.0	0.0	0.0
131891	BRD-A40787240	MDAMB231	0.01 uM	24 h	0.0	0.0	0.0	-0.3	-1.0	0.55
131916	BRD-A40787240	PC3	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131934	BRD-A40787240	THP1	2.22 uM	24 h	-0.26	-1.07	0.27	0.0	0.0	0.0

Summary