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CMap Candidate Details

Structure:
CMap ID: C02333
Pert ID: BRD-K43797669
Compound Name: genistein
Targets: CFTR|ESR1|ESR2|ESRRA|ESRRB|ESRRG|NCOA1|NCOA2|PPARG|PTK2B|TOP2A|TRPC5
MoA: tyrosine kinase inhibitor
SMILES: Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1139 BRD-K43797669 PC3 0.08 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
34109 BRD-K43797669 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35151 BRD-K43797669 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35571 BRD-K43797669 NEU 10 uM 24 h -0.26 -1.06 0.26 0.0 0.0 0.0
36270 BRD-K43797669 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36568 BRD-K43797669 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
56289 BRD-K43797669 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99149 BRD-K43797669 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
101214 BRD-K43797669 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119434 BRD-K43797669 A549 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
119500 BRD-K43797669 HCC515 1.11 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
119537 BRD-K43797669 HEPG2 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121585 BRD-K43797669 HA1E 10 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
129578 BRD-K43797669 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129595 BRD-K43797669 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129654 BRD-K43797669 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129717 BRD-K43797669 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).