CMap Candidate Details
Structure:
| CMap ID: | C02359 |
| Pert ID: | BRD-K34341643 |
| Compound Name: | glasdegib |
| Targets: | SMO |
| MoA: | hedgehog pathway inhibitor |
| SMILES: | CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120567 | BRD-K34341643 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120606 | BRD-K34341643 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.12 | 0.76 |
| 120672 | BRD-K34341643 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120725 | BRD-K34341643 | JURKAT | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120833 | BRD-K34341643 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.66 | 0.01 |
| 128990 | BRD-K34341643 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129039 | BRD-K34341643 | HELA | 0.08 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.63 |
| 129060 | BRD-K34341643 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.16 |
| 129083 | BRD-K34341643 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |