CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02360
Pert ID:	BRD-A61154809
Compound Name:	gliclazide
Targets:	ABCC8\|VEGFA
MoA:	ATP channel blocker; insulin secretagogue
SMILES:	Cc1ccc(cc1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
91399	BRD-A61154809	HUH7	10 uM	72 h	-0.21	-0.86	0.02	0.0	0.0	0.0
100247	BRD-A61154809	U2OS	10 uM	6 h	-0.23	-0.94	0.08	0.28	0.98	0.36
123819	BRD-A61154809	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123860	BRD-A61154809	A549	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123929	BRD-A61154809	HEK293	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124031	BRD-A61154809	JURKAT	1.11 uM	24 h	-0.23	-0.95	0.09	0.0	0.0	0.0
124082	BRD-A61154809	MCF10A	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124109	BRD-A61154809	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124146	BRD-A61154809	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.29	1.04	0.56
124159	BRD-A61154809	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124212	BRD-A61154809	THP1	1.11 uM	24 h	-0.22	-0.92	0.06	0.0	0.0	0.0
124265	BRD-A61154809	YAPC	3.33 uM	24 h	-0.17	-0.7	0.0	0.0	0.0	0.0
132182	BRD-A61154809	HA1E	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132214	BRD-A61154809	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.36	1.26	1.29
132245	BRD-A61154809	HT29	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary