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CMap Candidate Details

Structure:
CMap ID: C02375
Pert ID: BRD-K78303961
Compound Name: glycitein
Targets: TNF
MoA: tumor necrosis factor release inhibitor
SMILES: COc1cc2c(cc1O)occ(-c1ccc(O)cc1)c2=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127367 BRD-K78303961 A375 0.125 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.01
127444 BRD-K78303961 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
127476 BRD-K78303961 HELA 3.33 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
127489 BRD-K78303961 HT29 0.37 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
127534 BRD-K78303961 JURKAT 3.33 uM 24 h 0.22 0.91 0.03 -0.43 -1.43 15.35
127565 BRD-K78303961 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
127622 BRD-K78303961 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127659 BRD-K78303961 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127707 BRD-K78303961 YAPC 3.33 uM 24 h -0.2 -0.84 0.0 -0.2 -0.69 0.02
135351 BRD-K78303961 A549 0.74 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
135480 BRD-K78303961 MCF??7.00 0.01 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).