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CMap Candidate Details

Structure:
CMap ID: C02388
Pert ID: BRD-K19295594
Compound Name: gossypol
Targets: BCL2
MoA: BCL inhibitor; MCL1 inhibitor
SMILES: CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9380 BRD-K19295594 AGS 12 uM 6 h -0.28 -1.16 0.46 0.0 0.0 0.0
9691 BRD-K19295594 H1299 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10043 BRD-K19295594 HA1E 12 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
10159 BRD-K19295594 HCC515 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10753 BRD-K19295594 HEPG2 12 uM 6 h -0.28 -1.18 0.51 -0.42 -1.43 15.35
10958 BRD-K19295594 HT29 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11440 BRD-K19295594 NCIH2073 12 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
11731 BRD-K19295594 NCIH508 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12006 BRD-K19295594 NCIH596 12 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.27
12282 BRD-K19295594 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12483 BRD-K19295594 PC3 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12752 BRD-K19295594 SW480 12 uM 6 h 0.0 0.0 0.0 -0.43 -1.46 15.35
13234 BRD-K19295594 U937 12 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
13596 BRD-K19295594 VCAP 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87307 BRD-K19295594 BJAB 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
87367 BRD-K19295594 HBL1 10 uM 24 h 0.21 0.89 0.02 -0.33 -1.09 0.85
87417 BRD-K19295594 K562 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87465 BRD-K19295594 KMS34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87488 BRD-K19295594 MINO 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87569 BRD-K19295594 NALM6 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87619 BRD-K19295594 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87670 BRD-K19295594 OCILY19 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87721 BRD-K19295594 OCILY3 10 uM 24 h 0.22 0.9 0.03 0.0 0.0 0.0
87768 BRD-K19295594 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87791 BRD-K19295594 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87871 BRD-K19295594 TMD8 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.81 0.13
95517 BRD-K19295594 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95609 BRD-K19295594 MCF??7.00 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
95638 BRD-K19295594 U2OS 10 uM 24 h -0.21 -0.88 0.03 -0.45 -1.5 15.35
96633 BRD-K19295594 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).