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CMap Candidate Details

Structure:
CMap ID: C02403
Pert ID: BRD-K40578143
Compound Name: GR-79236
Targets: ADORA1|ADORA2A
MoA: adenosine receptor agonist
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@H]3CCC[C@@H]3O)ncnc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3021 BRD-K40578143 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3365 BRD-K40578143 HCC515 10 uM 6 h -0.23 -0.96 0.09 -0.39 -1.31 1.7
3501 BRD-K40578143 PC3 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
3793 BRD-K40578143 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44392 BRD-K40578143 A375 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
44585 BRD-K40578143 A549 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
44957 BRD-K40578143 ASC 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
45252 BRD-K40578143 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.14 1.01
45521 BRD-K40578143 HT29 10 uM 6 h -0.21 -0.89 0.03 -0.24 -0.8 0.12
45821 BRD-K40578143 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46072 BRD-K40578143 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46388 BRD-K40578143 PHH 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
46709 BRD-K40578143 SKB 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
99930 BRD-K40578143 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).