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CMap Candidate Details

Structure:
CMap ID: C00241
Pert ID: BRD-A11813248
Compound Name: AM-92016
Targets: GRIN1
MoA: potassium channel blocker
SMILES: CN(CCc1ccc(Cl)c(Cl)c1)CC(O)COc1ccc(NS(C)(=O)=O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2957 BRD-A11813248 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3087 BRD-A11813248 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3426 BRD-A11813248 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3664 BRD-A11813248 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44231 BRD-A11813248 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44474 BRD-A11813248 A549 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
44745 BRD-A11813248 ASC 10 uM 24 h -0.34 -1.43 1.43 0.0 0.0 0.0
45067 BRD-A11813248 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45348 BRD-A11813248 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45733 BRD-A11813248 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46177 BRD-A11813248 PHH 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.78
46493 BRD-A11813248 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).