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CMap Candidate Details

Structure:
CMap ID: C02417
Pert ID: BRD-K32847255
Compound Name: GSK-J1
Targets: KDM6B
MoA: histone demethylase inhibitor
SMILES: OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
93610 BRD-K32847255 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93682 BRD-K32847255 ASC 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93702 BRD-K32847255 CD34 3.33 uM 24 h -0.24 -0.99 0.14 0.32 1.15 0.88
93750 BRD-K32847255 HA1E 0.04 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
93786 BRD-K32847255 HCC515 1.11 uM 24 h 0.25 1.03 0.14 -0.24 -0.82 0.14
93830 BRD-K32847255 HEK293 0.04 uM 24 h 0.25 1.05 0.16 0.0 0.0 0.0
93877 BRD-K32847255 HELA 0.37 uM 24 h -0.27 -1.11 0.36 0.0 0.0 0.0
93918 BRD-K32847255 HEPG2 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93955 BRD-K32847255 HUVEC 0.12 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
94014 BRD-K32847255 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94055 BRD-K32847255 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94094 BRD-K32847255 NEU 1.11 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
94155 BRD-K32847255 NPC 3.33 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
94190 BRD-K32847255 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94227 BRD-K32847255 SHSY5Y 0.12 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
94278 BRD-K32847255 SKL 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94329 BRD-K32847255 THP1 0.12 uM 24 h 0.23 0.96 0.07 0.23 0.82 0.1
94373 BRD-K32847255 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).