CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02418
Pert ID:	BRD-K82484347
Compound Name:	GSK-J2
Targets:
MoA:	histone demethylase inhibitor
SMILES:	OC(=O)CCNc1cc(nc(n1)-c1cccnc1)N1CCc2ccccc2CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
93632	BRD-K82484347	A549	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93675	BRD-K82484347	ASC	10 uM	24 h	0.0	0.0	0.0	-0.21	-0.72	0.04
93740	BRD-K82484347	CD34	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93774	BRD-K82484347	HA1E	10 uM	24 h	-0.28	-1.17	0.48	0.0	0.0	0.0
93814	BRD-K82484347	HCC515	1.11 uM	24 h	-0.21	-0.88	0.03	-0.23	-0.78	0.1
93865	BRD-K82484347	HEK293	1.11 uM	24 h	0.0	0.0	0.0	0.26	0.93	0.28
93905	BRD-K82484347	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93947	BRD-K82484347	HEPG2	0.04 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.64
93974	BRD-K82484347	HUVEC	10 uM	24 h	-0.28	-1.16	0.47	0.0	0.0	0.0
94048	BRD-K82484347	JURKAT	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94077	BRD-K82484347	MCF??7.00	0.12 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94128	BRD-K82484347	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94165	BRD-K82484347	NPC	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94208	BRD-K82484347	PC3	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94263	BRD-K82484347	SHSY5Y	0.12 uM	24 h	-0.24	-0.99	0.13	-0.17	-0.57	0.0
94314	BRD-K82484347	SKL	1.11 uM	24 h	0.22	0.9	0.03	0.29	1.02	0.49
94358	BRD-K82484347	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94396	BRD-K82484347	YAPC	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary