CMap Candidate Details
Structure:
| CMap ID: | C02428 |
| Pert ID: | BRD-K06750613 |
| Compound Name: | GSK1059615 |
| Targets: | PIK3CG |
| MoA: | PI3K inhibitor |
| SMILES: | O=C1NC(=O)\C(S1)=C\c1ccc2nccc(-c3ccncc3)c2c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49803 | BRD-K06750613 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50144 | BRD-K06750613 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50332 | BRD-K06750613 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.91 | 0.24 |
| 51123 | BRD-K06750613 | VCAP | 10 uM | 6 h | 0.18 | 0.73 | 0.0 | -0.18 | -0.6 | 0.0 |
| 96060 | BRD-K06750613 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.32 | 1.71 |
| 97325 | BRD-K06750613 | HAP1 | 0.66 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.93 | 0.35 |
| 117689 | BRD-K06750613 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117834 | BRD-K06750613 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117884 | BRD-K06750613 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.21 | 0.76 | 0.05 |
| 117932 | BRD-K06750613 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117980 | BRD-K06750613 | PC3 | 0.37 uM | 24 h | 0.26 | 1.09 | 0.23 | -0.33 | -1.12 | 0.93 |