CMap Candidate Details
Structure:
| CMap ID: | C02459 |
| Pert ID: | BRD-K89015388 |
| Compound Name: | GSK923295 |
| Targets: | CENPE |
| MoA: | centromere associated protein inhibitor |
| SMILES: | CC(C)Oc1ccc(cc1Cl)C(=O)N[C@H](CNC(=O)CN(C)C)Cc1ccc(cc1)-c1cn2cccc([C@H](C)O)c2n1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121739 | BRD-K89015388 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121820 | BRD-K89015388 | MCF??7.00 | 1.11 uM | 24 h | 0.2 | 0.82 | 0.0 | -0.27 | -0.9 | 0.28 |
| 121847 | BRD-K89015388 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.23 | 1.25 |
| 129761 | BRD-K89015388 | A375 | 2.22 uM | 24 h | 0.22 | 0.91 | 0.04 | -0.24 | -0.82 | 0.15 |
| 129838 | BRD-K89015388 | HEK293 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129876 | BRD-K89015388 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.16 |
| 129899 | BRD-K89015388 | HT29 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.11 |
| 129922 | BRD-K89015388 | JURKAT | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129964 | BRD-K89015388 | MCF10A | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130049 | BRD-K89015388 | MDAMB231 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130120 | BRD-K89015388 | THP1 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130166 | BRD-K89015388 | YAPC | 2.22 uM | 24 h | -0.28 | -1.16 | 0.47 | -0.36 | -1.21 | 1.24 |