CMap Candidate Details
Structure:
| CMap ID: | C02467 |
| Pert ID: | BRD-K62676709 |
| Compound Name: | guanethidine |
| Targets: | SLC6A2 |
| MoA: | adrenergic inhibitor |
| SMILES: | NC(=N)NCCN1CCCCCCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 124960 | BRD-K62676709 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.16 |
| 124993 | BRD-K62676709 | HA1E | 0.04 uM | 24 h | -0.22 | -0.93 | 0.07 | 0.0 | 0.0 | 0.0 |
| 125020 | BRD-K62676709 | HELA | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125070 | BRD-K62676709 | MCF10A | 1.11 uM | 24 h | 0.18 | 0.74 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125105 | BRD-K62676709 | MDAMB231 | 1.11 uM | 24 h | 0.38 | 1.59 | 1.52 | 0.0 | 0.0 | 0.0 |
| 125152 | BRD-K62676709 | THP1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132974 | BRD-K62676709 | A375 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133038 | BRD-K62676709 | HEK293 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.41 |
| 133110 | BRD-K62676709 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.11 | 0.72 |
| 133145 | BRD-K62676709 | JURKAT | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133218 | BRD-K62676709 | MCF??7.00 | 2.22 uM | 24 h | -0.25 | -1.03 | 0.19 | -0.35 | -1.18 | 1.14 |
| 133284 | BRD-K62676709 | PC3 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133311 | BRD-K62676709 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |