CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02485
Pert ID:	BRD-K14880289
Compound Name:	GW-501516
Targets:	PPARA\|PPARD
MoA:	PPAR receptor agonist
SMILES:	Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1212	BRD-K14880289	PC3	10 uM	24 h	0.0	0.0	0.0	0.36	1.29	1.49
1254	BRD-K14880289	A549	10 uM	48 h	0.0	0.0	0.0	-0.35	-1.18	1.14
1359	BRD-K14880289	U2OS	0.12 uM	48 h	0.21	0.88	0.01	0.0	0.0	0.0
33731	BRD-K14880289	A375	10 uM	6 h	0.0	0.0	0.0	-0.27	-0.89	0.27
34052	BRD-K14880289	ASC	10 uM	24 h	0.21	0.87	0.01	-0.29	-0.96	0.44
34321	BRD-K14880289	HA1E	10 uM	6 h	0.21	0.89	0.02	0.0	0.0	0.0
34567	BRD-K14880289	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34836	BRD-K14880289	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.41	-1.37	2.02
35101	BRD-K14880289	HT29	10 uM	6 h	-0.21	-0.88	0.03	0.0	0.0	0.0
35495	BRD-K14880289	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35545	BRD-K14880289	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
35737	BRD-K14880289	NPC	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.88
36210	BRD-K14880289	PHH	10 uM	24 h	0.0	0.0	0.0	0.32	1.12	0.77
36505	BRD-K14880289	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36782	BRD-K14880289	VCAP	10 uM	24 h	0.16	0.67	0.0	-0.17	-0.58	0.0

Summary