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CMap Candidate Details

Structure:
CMap ID: C02486
Pert ID: BRD-K39520573
Compound Name: GW-5074
Targets: NTRK1|RAF1
MoA: RAF inhibitor; leucine rich repeat kinase inhibitor
SMILES: Oc1c(Br)cc(C=C2C(=O)Nc3ccc(I)cc23)cc1Br
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6743 BRD-K39520573 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6991 BRD-K39520573 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7313 BRD-K39520573 HA1E 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
7650 BRD-K39520573 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.6
7860 BRD-K39520573 HT29 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.59
8088 BRD-K39520573 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
8365 BRD-K39520573 PC3 10 uM 24 h 0.28 1.19 0.41 0.0 0.0 0.0
8669 BRD-K39520573 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).