CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02494
Pert ID:	BRD-K26823213
Compound Name:	GW-842166
Targets:	CNR2
MoA:	cannabinoid receptor agonist
SMILES:	FC(F)(F)c1nc(Nc2ccc(Cl)cc2Cl)ncc1C(=O)NCC1CCOCC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
121932	BRD-K26823213	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.05	0.72
121950	BRD-K26823213	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121976	BRD-K26823213	HELA	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121999	BRD-K26823213	HT29	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.35
122033	BRD-K26823213	HUVEC	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122099	BRD-K26823213	MCF??7.00	0.04 uM	24 h	-0.32	-1.33	0.89	0.0	0.0	0.0
122133	BRD-K26823213	MDAMB231	0.37 uM	24 h	0.0	0.0	0.0	0.21	0.74	0.03
122156	BRD-K26823213	PC3	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.11	0.9
130180	BRD-K26823213	A375	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130194	BRD-K26823213	A549	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130335	BRD-K26823213	JURKAT	0.74 uM	24 h	-0.25	-1.05	0.23	0.0	0.0	0.0
130387	BRD-K26823213	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130490	BRD-K26823213	THP1	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130515	BRD-K26823213	YAPC	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary