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CMap Candidate Details

Structure:
CMap ID: C00250
Pert ID: BRD-K42948882
Compound Name: AMD11070
Targets: CXCR4
MoA: CC chemokine receptor antagonist
SMILES: NCCCCN(Cc1nc2ccccc2[nH]1)[C@H]1CCCc2cccnc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123245 BRD-K42948882 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123265 BRD-K42948882 A549 10 uM 24 h -0.18 -0.75 0.0 0.0 0.0 0.0
123319 BRD-K42948882 HELA 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.39
123352 BRD-K42948882 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123372 BRD-K42948882 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123432 BRD-K42948882 PC3 0.125 uM 24 h 0.27 1.14 0.31 0.3 1.06 0.59
123469 BRD-K42948882 THP1 10 uM 24 h -0.24 -1.02 0.18 0.3 1.07 0.63
123502 BRD-K42948882 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.18 0.65 0.01
131598 BRD-K42948882 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131639 BRD-K42948882 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131739 BRD-K42948882 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131793 BRD-K42948882 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.09
131868 BRD-K42948882 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.19 0.68 0.01
131900 BRD-K42948882 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).