CMap Candidate Details
Structure:
| CMap ID: | C02585 |
| Pert ID: | BRD-A99117172 |
| Compound Name: | hydroxychloroquine |
| Targets: | TLR7|TLR9 |
| MoA: | antimalarial agent |
| SMILES: | CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 484 | BRD-A99117172 | BJAB | 0.66 uM | 24 h | 0.28 | 1.16 | 0.35 | 0.0 | 0.0 | 0.0 |
| 528 | BRD-A99117172 | HBL1 | 0.66 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.05 | 0.57 |
| 570 | BRD-A99117172 | K562 | 10 uM | 24 h | -0.22 | -0.93 | 0.07 | -0.28 | -0.95 | 0.41 |
| 622 | BRD-A99117172 | KMS34 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.31 |
| 667 | BRD-A99117172 | MINO | 0.66 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 715 | BRD-A99117172 | NALM6 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 784 | BRD-A99117172 | OCILY19 | 0.04 uM | 4 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 826 | BRD-A99117172 | OCILY3 | 10 uM | 4 h | -0.21 | -0.88 | 0.03 | 0.0 | 0.0 | 0.0 |
| 856 | BRD-A99117172 | SKMEL5 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.37 | 1.31 | 1.59 |
| 902 | BRD-A99117172 | THP1 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 935 | BRD-A99117172 | TMD8 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51580 | BRD-A99117172 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.77 | 0.06 |
| 51793 | BRD-A99117172 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.41 |
| 98988 | BRD-A99117172 | NEU | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99121 | BRD-A99117172 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |