CMap Candidate Details
Structure:
| CMap ID: | C02586 |
| Pert ID: | BRD-K77793136 |
| Compound Name: | hydroxyfasudil |
| Targets: | PKIA|PRKACA|ROCK1 |
| MoA: | rho associated kinase inhibitor |
| SMILES: | Oc1nccc2c(cccc12)S(=O)(=O)N1CCCNCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 7024 | BRD-K77793136 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7481 | BRD-K77793136 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7712 | BRD-K77793136 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7911 | BRD-K77793136 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.77 | 0.05 |
| 8284 | BRD-K77793136 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.18 | -0.61 | 0.0 |
| 8844 | BRD-K77793136 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.9 | 0.29 |
| 96980 | BRD-K77793136 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.93 |
| 97059 | BRD-K77793136 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |