CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02596
Pert ID:	BRD-K46424862
Compound Name:	hymecromone
Targets:	MAOA\|MAOB
MoA:	monoamine oxidase inhibitor
SMILES:	Cc1cc(=O)oc2cc(O)ccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6998	BRD-K46424862	A549	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.87
7662	BRD-K46424862	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
8509	BRD-K46424862	PC3	10 uM	6 h	-0.25	-1.05	0.24	0.3	1.07	0.63
8819	BRD-K46424862	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
125303	BRD-K46424862	HEK293	0.04 uM	24 h	0.0	0.0	0.0	-0.17	-0.56	0.0
125394	BRD-K46424862	JURKAT	0.04 uM	24 h	-0.16	-0.66	0.0	0.22	0.77	0.05
125438	BRD-K46424862	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	0.28	0.99	0.39
133334	BRD-K46424862	A375	0.01 uM	24 h	0.25	1.04	0.15	0.29	1.03	0.5
133384	BRD-K46424862	HA1E	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133413	BRD-K46424862	HELA	0.03 uM	24 h	0.23	0.97	0.08	-0.35	-1.17	1.12
133448	BRD-K46424862	HT29	0.03 uM	24 h	0.28	1.15	0.33	0.0	0.0	0.0
133509	BRD-K46424862	MCF10A	0.08 uM	24 h	0.21	0.86	0.01	0.0	0.0	0.0
133546	BRD-K46424862	MDAMB231	0.03 uM	24 h	0.0	0.0	0.0	-0.38	-1.3	1.57
133602	BRD-K46424862	THP1	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133624	BRD-K46424862	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary