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CMap Candidate Details

Structure:
CMap ID: C02598
Pert ID: BRD-K40530731
Compound Name: hyoscyamine
Targets: CHRM1|CHRM2|CHRM3|CHRM4
MoA: acetylcholine receptor antagonist
SMILES: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)[C@H](CO)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3020 BRD-K40530731 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3198 BRD-K40530731 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3621 BRD-K40530731 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3961 BRD-K40530731 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44391 BRD-K40530731 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44584 BRD-K40530731 A549 10 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
44956 BRD-K40530731 ASC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
45251 BRD-K40530731 HEPG2 10 uM 6 h 0.21 0.88 0.01 0.0 0.0 0.0
45520 BRD-K40530731 HT29 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.86
45820 BRD-K40530731 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46071 BRD-K40530731 NPC 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
46387 BRD-K40530731 PHH 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
46708 BRD-K40530731 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).