CMap Candidate Details
Structure:
| CMap ID: | C02609 |
| Pert ID: | BRD-K57090026 |
| Compound Name: | I-CBP-112 |
| Targets: | CREBBP|EP300 |
| MoA: | bromodomain inhibitor |
| SMILES: | CCC(=O)N1CCOc2c(C1)cc(cc2OC[C@H]1CCCN(C)C1)-c1ccc(OC)c(OC)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96726 | BRD-K57090026 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96777 | BRD-K57090026 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.41 | -1.39 | 2.02 |
| 118733 | BRD-K57090026 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118769 | BRD-K57090026 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.09 | 0.83 |
| 118810 | BRD-K57090026 | HCC515 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.8 | 0.11 |
| 118852 | BRD-K57090026 | HEPG2 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118893 | BRD-K57090026 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118932 | BRD-K57090026 | MCF??7.00 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |