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CMap Candidate Details

Structure:
CMap ID: C02612
Pert ID: BRD-K15196155
Compound Name: IBC-293
Targets: HCAR3
MoA: hydroxycarboxylic acid receptor agonist
SMILES: CC(C)n1nnc2cc(ccc12)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4067 BRD-K15196155 HA1E 10 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
4374 BRD-K15196155 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4782 BRD-K15196155 PC3 10 uM 6 h 0.2 0.81 0.0 -0.31 -1.03 0.62
5043 BRD-K15196155 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44315 BRD-K15196155 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44529 BRD-K15196155 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
45174 BRD-K15196155 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45442 BRD-K15196155 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45779 BRD-K15196155 MCF??7.00 10 uM 6 h 0.22 0.92 0.04 0.24 0.84 0.13
45986 BRD-K15196155 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46305 BRD-K15196155 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46619 BRD-K15196155 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
100130 BRD-K15196155 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).