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CMap Candidate Details

Structure:
CMap ID: C02634
Pert ID: BRD-K29133151
Compound Name: ICI-185,282
Targets:
MoA: thromboxane receptor antagonist
SMILES: OC(=O)CCC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96542 BRD-K29133151 PC3 10 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
99808 BRD-K29133151 U2OS 10 uM 6 h 0.18 0.73 0.0 0.0 0.0 0.0
115231 BRD-K29133151 A375 3.33 uM 24 h -0.24 -1.0 0.15 0.0 0.0 0.0
115373 BRD-K29133151 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115425 BRD-K29133151 HEPG2 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122014 BRD-K29133151 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122060 BRD-K29133151 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122114 BRD-K29133151 MCF??7.00 3.33 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
130207 BRD-K29133151 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130237 BRD-K29133151 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130261 BRD-K29133151 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130296 BRD-K29133151 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130361 BRD-K29133151 JURKAT 2.22 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
130408 BRD-K29133151 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.59
130456 BRD-K29133151 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130498 BRD-K29133151 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130530 BRD-K29133151 YAPC 2.22 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).