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CMap Candidate Details

Structure:
CMap ID: C02638
Pert ID: BRD-K52219182
Compound Name: ICI-63197
Targets:
MoA: phosphodiesterase inhibitor
SMILES: CCCn1c2nc(N)nn2cc(C)c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5463 BRD-K52219182 HA1E 10 uM 6 h 0.0 0.0 0.0 0.32 1.15 0.87
5646 BRD-K52219182 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5928 BRD-K52219182 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6035 BRD-K52219182 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6432 BRD-K52219182 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37296 BRD-K52219182 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37687 BRD-K52219182 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38210 BRD-K52219182 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38510 BRD-K52219182 NPC 10 uM 24 h 0.17 0.7 0.0 0.29 1.03 0.51
38742 BRD-K52219182 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38971 BRD-K52219182 SKB 10 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
96990 BRD-K52219182 A375 10 uM 24 h 0.28 1.16 0.35 0.0 0.0 0.0
97068 BRD-K52219182 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).