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CMap Candidate Details

Structure:
CMap ID: C02642
Pert ID: BRD-K47192521
Compound Name: icosapent
Targets: ACSL3|ACSL4|FADS1|FFAR1|PPARD|PPARG|PTGS1|PTGS2|SLC8A1|TRPV1
MoA: platelet aggregation inhibitor
SMILES: CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6759 BRD-K47192521 A375 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.44
7001 BRD-K47192521 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
7328 BRD-K47192521 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7666 BRD-K47192521 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7872 BRD-K47192521 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8098 BRD-K47192521 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
8511 BRD-K47192521 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8685 BRD-K47192521 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98757 BRD-K47192521 NPC 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.69 0.03
98903 BRD-K47192521 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99574 BRD-K47192521 U2OS 1.11 uM 6 h 0.22 0.93 0.05 0.2 0.73 0.03
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).