CMap Candidate Details
Structure:
| CMap ID: | C02648 |
| Pert ID: | BRD-K79102359 |
| Compound Name: | idalopirdine |
| Targets: | HTR6 |
| MoA: | serotonin receptor antagonist |
| SMILES: | FC(F)C(F)(F)COc1cccc(CNCCc2c[nH]c3cc(F)ccc23)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127372 | BRD-K79102359 | A375 | 10 uM | 24 h | 0.21 | 0.87 | 0.01 | 0.0 | 0.0 | 0.0 |
| 127405 | BRD-K79102359 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127449 | BRD-K79102359 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.85 | 0.14 |
| 127477 | BRD-K79102359 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.23 |
| 127492 | BRD-K79102359 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.2 |
| 127539 | BRD-K79102359 | JURKAT | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127566 | BRD-K79102359 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127586 | BRD-K79102359 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |
| 127627 | BRD-K79102359 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.25 | 1.29 |
| 127662 | BRD-K79102359 | THP1 | 10 uM | 24 h | -0.3 | -1.24 | 0.67 | -0.23 | -0.78 | 0.09 |
| 127712 | BRD-K79102359 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |