CMap Candidate Details
Structure:
| CMap ID: | C02649 |
| Pert ID: | BRD-K69650333 |
| Compound Name: | idarubicin |
| Targets: | TOP2A |
| MoA: | topoisomerase inhibitor |
| SMILES: | C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24472 | BRD-K69650333 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.36 | 1.28 | 1.34 |
| 24602 | BRD-K69650333 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24803 | BRD-K69650333 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.15 | 0.9 |
| 24939 | BRD-K69650333 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.02 | 0.47 |
| 25038 | BRD-K69650333 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25182 | BRD-K69650333 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25528 | BRD-K69650333 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |