CMap Candidate Details
Structure:
| CMap ID: | C00265 |
| Pert ID: | BRD-K43802723 |
| Compound Name: | AMG-837 |
| Targets: | FFAR1 |
| MoA: | free fatty acid receptor agonist |
| SMILES: | CC#C[C@@H](CC(O)=O)c1ccc(OCc2cccc(c2)-c2ccc(cc2)C(F)(F)F)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121548 | BRD-K43802723 | A375 | 10 uM | 24 h | -0.24 | -0.99 | 0.14 | 0.0 | 0.0 | 0.0 |
| 121583 | BRD-K43802723 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121628 | BRD-K43802723 | HELA | 0.125 uM | 24 h | -0.24 | -1.01 | 0.16 | 0.0 | 0.0 | 0.0 |
| 121653 | BRD-K43802723 | HT29 | 1.11 uM | 24 h | 0.22 | 0.93 | 0.05 | 0.0 | 0.0 | 0.0 |
| 121670 | BRD-K43802723 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.05 |
| 121696 | BRD-K43802723 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129676 | BRD-K43802723 | PC3 | 0.03 uM | 24 h | 0.25 | 1.06 | 0.18 | 0.0 | 0.0 | 0.0 |