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CMap Candidate Details

Structure:
CMap ID: C02667
Pert ID: BRD-K26373640
Compound Name: IKK-2-inhibitor
Targets: IKBKB
MoA: IKK inhibitor; SYK inhibitor
SMILES: NC(=O)c1sc(cc1N)-c1ccsc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4087 BRD-K26373640 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
4399 BRD-K26373640 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4793 BRD-K26373640 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5061 BRD-K26373640 VCAP 10 uM 6 h 0.0 0.0 0.0 0.43 1.51 2.27
44350 BRD-K26373640 A375 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.37
44908 BRD-K26373640 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45212 BRD-K26373640 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.84
45478 BRD-K26373640 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45673 BRD-K26373640 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46027 BRD-K26373640 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46345 BRD-K26373640 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46661 BRD-K26373640 SKB 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
96126 BRD-K26373640 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99779 BRD-K26373640 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).