CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02672
Pert ID:	BRD-A45664787
Compound Name:	iloprost
Targets:	PDE4A\|PDE4B\|PDE4C\|PDE4D\|PLAT\|PTGDR\|PTGER1\|PTGER2\|PTGER3\|PTGER4\|PTGFR\|PTGIR\|TBXA2R
MoA:	platelet aggregation inhibitor; prostanoid receptor agonist
SMILES:	CC#CCC(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2C\C(C[C@H]12)=C/CCCC(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1000	BRD-A45664787	CD34	10 uM	6 h	-0.34	-1.43	1.43	-0.45	-1.51	15.35
1060	BRD-A45664787	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
1120	BRD-A45664787	U937	0.37 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
29729	BRD-A45664787	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
30303	BRD-A45664787	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
30631	BRD-A45664787	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
30914	BRD-A45664787	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
31209	BRD-A45664787	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
31712	BRD-A45664787	HT29	10 uM	6 h	0.0	0.0	0.0	-0.25	-0.83	0.17
31806	BRD-A45664787	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
32297	BRD-A45664787	NPC	10 uM	24 h	-0.27	-1.11	0.37	0.0	0.0	0.0
32891	BRD-A45664787	SKB	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.06	0.73
33206	BRD-A45664787	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.08	0.78
91208	BRD-A45664787	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
96084	BRD-A45664787	A549	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24

Summary