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CMap Candidate Details

Structure:
CMap ID: C02690
Pert ID: BRD-K33308633
Compound Name: INCA-6
Targets: NFATC1
MoA: calcineurin inhibitor
SMILES: O=C1C=CC(=O)C2=C1C1c3ccccc3C2c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5200 BRD-K33308633 A375 10 uM 6 h 0.18 0.76 0.0 0.0 0.0 0.0
5317 BRD-K33308633 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5611 BRD-K33308633 HCC515 10 uM 24 h -0.3 -1.24 0.64 0.0 0.0 0.0
5902 BRD-K33308633 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6016 BRD-K33308633 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6179 BRD-K33308633 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6378 BRD-K33308633 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44566 BRD-K33308633 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44929 BRD-K33308633 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45686 BRD-K33308633 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
46047 BRD-K33308633 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
46364 BRD-K33308633 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46683 BRD-K33308633 SKB 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
99854 BRD-K33308633 U2OS 10 uM 6 h 0.32 1.33 0.84 -0.31 -1.06 0.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).