CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02694
Pert ID:	BRD-K89208535
Compound Name:	indacaterol
Targets:	ADRB1\|ADRB2
MoA:	adrenergic receptor agonist
SMILES:	CCc1cc2CC(Cc2cc1CC)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
127731	BRD-K89208535	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127773	BRD-K89208535	A549	10 uM	24 h	0.23	0.96	0.08	0.28	0.99	0.41
127813	BRD-K89208535	HA1E	1.11 uM	24 h	0.25	1.04	0.14	0.0	0.0	0.0
127851	BRD-K89208535	HEK293	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127897	BRD-K89208535	HT29	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.02	0.59
127925	BRD-K89208535	HUVEC	10 uM	24 h	-0.22	-0.91	0.06	0.0	0.0	0.0
127979	BRD-K89208535	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.02	0.6
128022	BRD-K89208535	MCF??7.00	10 uM	24 h	-0.23	-0.96	0.1	-0.41	-1.39	2.02
128043	BRD-K89208535	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128070	BRD-K89208535	YAPC	10 uM	24 h	0.0	0.0	0.0	0.39	1.38	2.16
135552	BRD-K89208535	HELA	2.22 uM	24 h	0.31	1.3	0.72	0.0	0.0	0.0
135643	BRD-K89208535	JURKAT	0.74 uM	24 h	0.0	0.0	0.0	-0.25	-0.86	0.2

Summary