CMap Candidate Details
Structure:
| CMap ID: | C02700 |
| Pert ID: | BRD-K33226500 |
| Compound Name: | indinavir |
| Targets: | CYP3A4|CYP3A5|CYP3A7 |
| MoA: | HIV protease inhibitor |
| SMILES: | CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1235 | BRD-K33226500 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1370 | BRD-K33226500 | U2OS | 0.12 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25016 | BRD-K33226500 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.93 | 0.27 |
| 25502 | BRD-K33226500 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96635 | BRD-K33226500 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96700 | BRD-K33226500 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.63 | 0.01 |
| 120659 | BRD-K33226500 | HT29 | 0.04 uM | 24 h | -0.23 | -0.96 | 0.1 | 0.0 | 0.0 | 0.0 |
| 120712 | BRD-K33226500 | JURKAT | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120820 | BRD-K33226500 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.89 | 0.27 |
| 129005 | BRD-K33226500 | HA1E | 0.25 uM | 24 h | -0.21 | -0.87 | 0.02 | 0.24 | 0.85 | 0.15 |
| 129020 | BRD-K33226500 | HELA | 0.74 uM | 24 h | 0.29 | 1.2 | 0.42 | 0.0 | 0.0 | 0.0 |