CMap Candidate Details
Structure:
| CMap ID: | C02702 |
| Pert ID: | BRD-K17894950 |
| Compound Name: | indirubin |
| Targets: | CDK1|CDK5|GSK3A |
| MoA: | CDK inhibitor; glycogen synthase kinase inhibitor |
| SMILES: | O=C1Nc2ccccc2\C1=C1\Nc2ccccc2C1=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 7630 | BRD-K17894950 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.15 |
| 7841 | BRD-K17894950 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.71 | 0.03 |
| 8650 | BRD-K17894950 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53227 | BRD-K17894950 | MCF10A | 30 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.05 | 0.57 |
| 95312 | BRD-K17894950 | A549 | 0.12 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95346 | BRD-K17894950 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.96 | 0.42 |
| 95454 | BRD-K17894950 | U2OS | 0.12 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96439 | BRD-K17894950 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96506 | BRD-K17894950 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.03 | 0.52 |
| 120494 | BRD-K17894950 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128910 | BRD-K17894950 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128930 | BRD-K17894950 | HELA | 0.74 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |