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CMap Candidate Details

Structure:
CMap ID: C02709
Pert ID: BRD-K01815685
Compound Name: indole-3-carbinol
Targets: AHR
MoA: aryl hydrocarbon receptor agonist; indoleamine 2,3-dioxygenase inhibitor
SMILES: OCc1c[nH]c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4039 BRD-K01815685 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4337 BRD-K01815685 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4874 BRD-K01815685 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37575 BRD-K01815685 ASC 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
38414 BRD-K01815685 NPC 10 uM 24 h 0.21 0.87 0.01 -0.2 -0.66 0.01
38903 BRD-K01815685 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52446 BRD-K01815685 PC3 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
52949 BRD-K01815685 HEPG2 40 uM 3 h 0.19 0.8 0.0 0.0 0.0 0.0
99963 BRD-K01815685 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
122897 BRD-K01815685 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.19
122973 BRD-K01815685 HT29 0.125 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
123022 BRD-K01815685 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123075 BRD-K01815685 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123111 BRD-K01815685 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123183 BRD-K01815685 THP1 10 uM 24 h 0.28 1.16 0.36 0.0 0.0 0.0
131210 BRD-K01815685 A375 2.22 uM 24 h -0.22 -0.93 0.07 -0.26 -0.87 0.22
131246 BRD-K01815685 A549 0.08 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
131306 BRD-K01815685 HELA 0.03 uM 24 h 0.24 1.02 0.12 -0.21 -0.72 0.04
131359 BRD-K01815685 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131399 BRD-K01815685 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131497 BRD-K01815685 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).