Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02732
Pert ID: BRD-K51918615
Compound Name: iodophenpropit
Targets: HRH3|HRH4
MoA: histamine receptor antagonist
SMILES: Ic1ccc(CCNC(=N)SCCCc2c[nH]cn2)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2895 BRD-K51918615 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3225 BRD-K51918615 HCC515 10 uM 24 h -0.22 -0.9 0.04 0.4 1.4 2.18
3521 BRD-K51918615 PC3 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.08
3826 BRD-K51918615 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41783 BRD-K51918615 A375 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
42102 BRD-K51918615 A549 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.13
42383 BRD-K51918615 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42704 BRD-K51918615 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43006 BRD-K51918615 HT29 10 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.18
43325 BRD-K51918615 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43571 BRD-K51918615 NPC 10 uM 24 h 0.2 0.84 0.0 -0.3 -1.03 0.62
43871 BRD-K51918615 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44130 BRD-K51918615 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).