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CMap Candidate Details

Structure:
CMap ID: C02768
Pert ID: BRD-K93332168
Compound Name: isocarboxazid
Targets: MAOA|MAOB
MoA: monoamine oxidase inhibitor
SMILES: Cc1cc(no1)C(=O)NNCc1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2945 BRD-K93332168 HA1E 10 uM 24 h 0.19 0.8 0.0 0.28 1.0 0.42
3292 BRD-K93332168 HCC515 10 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
3898 BRD-K93332168 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
39233 BRD-K93332168 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39526 BRD-K93332168 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39837 BRD-K93332168 ASC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
40126 BRD-K93332168 HEPG2 10 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
40386 BRD-K93332168 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40933 BRD-K93332168 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41259 BRD-K93332168 NPC 10 uM 24 h -0.3 -1.23 0.63 0.0 0.0 0.0
41598 BRD-K93332168 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51650 BRD-K93332168 MCF??7.00 10 uM 24 h -0.21 -0.87 0.02 -0.31 -1.04 0.68
51864 BRD-K93332168 PC3 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).