CMap Candidate Details
Structure:
| CMap ID: | C02780 |
| Pert ID: | BRD-K87202646 |
| Compound Name: | isoniazid |
| Targets: | CYP1A2|CYP2C19|CYP2C8|CYP2E1|CYP3A4 |
| MoA: | FABI inhibitor |
| SMILES: | NNC(=O)c1ccncc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 52618 | BRD-K87202646 | A549 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 52786 | BRD-K87202646 | HEPG2 | 40 uM | 24 h | -0.2 | -0.85 | 0.01 | 0.0 | 0.0 | 0.0 |
| 53373 | BRD-K87202646 | MCF10A | 12 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91058 | BRD-K87202646 | HUH7 | 25 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121724 | BRD-K87202646 | A375 | 0.04 uM | 24 h | -0.2 | -0.83 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121742 | BRD-K87202646 | HA1E | 0.04 uM | 24 h | 0.28 | 1.17 | 0.36 | 0.0 | 0.0 | 0.0 |
| 121774 | BRD-K87202646 | HELA | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.31 | 1.69 |
| 121805 | BRD-K87202646 | HT29 | 0.04 uM | 24 h | 0.24 | 1.01 | 0.12 | 0.0 | 0.0 | 0.0 |
| 129846 | BRD-K87202646 | HEK293 | 0.03 uM | 24 h | -0.31 | -1.28 | 0.77 | 0.23 | 0.82 | 0.1 |
| 130010 | BRD-K87202646 | MCF??7.00 | 0.08 uM | 24 h | -0.3 | -1.23 | 0.63 | 0.0 | 0.0 | 0.0 |
| 130057 | BRD-K87202646 | MDAMB231 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.77 | 0.08 |
| 130088 | BRD-K87202646 | PC3 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130128 | BRD-K87202646 | THP1 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130171 | BRD-K87202646 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.16 |