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CMap Candidate Details

Structure:
CMap ID: C00280
Pert ID: BRD-K64931368
Compound Name: aminocaproic-acid
Targets: LPA|PLAT|PLG
MoA: plasminogen activator inhibitor
SMILES: NCCCCCC(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52183 BRD-K64931368 MCF??7.00 10 uM 6 h 0.16 0.68 0.0 0.0 0.0 0.0
124663 BRD-K64931368 HELA 3.33 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
124726 BRD-K64931368 JURKAT 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
124801 BRD-K64931368 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124842 BRD-K64931368 PC3 10 uM 24 h -0.2 -0.85 0.01 -0.22 -0.74 0.06
132664 BRD-K64931368 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132692 BRD-K64931368 A549 0.03 uM 24 h 0.24 1.02 0.13 0.25 0.88 0.18
132723 BRD-K64931368 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
132759 BRD-K64931368 HEK293 0.01 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
132812 BRD-K64931368 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132874 BRD-K64931368 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
132933 BRD-K64931368 THP1 0.74 uM 24 h -0.32 -1.33 0.93 0.0 0.0 0.0
132955 BRD-K64931368 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).