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CMap Candidate Details

Structure:
CMap ID: C02805
Pert ID: BRD-K60298136
Compound Name: ITE
Targets: AHR
MoA: aryl hydrocarbon receptor agonist
SMILES: COC(=O)c1csc(n1)C(=O)c1c[nH]c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2910 BRD-K60298136 HA1E 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.05
3242 BRD-K60298136 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
3530 BRD-K60298136 PC3 10 uM 24 h 0.25 1.04 0.15 0.25 0.88 0.19
3842 BRD-K60298136 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41802 BRD-K60298136 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41956 BRD-K60298136 A549 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.31
42410 BRD-K60298136 ASC 10 uM 24 h -0.28 -1.16 0.45 0.28 1.0 0.43
43028 BRD-K60298136 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43335 BRD-K60298136 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
43896 BRD-K60298136 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52973 BRD-K60298136 HEPG2 20 uM 3 h 0.0 0.0 0.0 0.28 0.97 0.36
53199 BRD-K60298136 MCF10A 30 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.09
99713 BRD-K60298136 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).