CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00281
Pert ID:	BRD-A25234499
Compound Name:	aminoglutethimide
Targets:	CYP11A1\|CYP19A1
MoA:	glucocorticoid receptor antagonist
SMILES:	CCC1(CCC(=O)NC1=O)c1ccc(N)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
19863	BRD-A25234499	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
20189	BRD-A25234499	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
20997	BRD-A25234499	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
21677	BRD-A25234499	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.35	-1.17	1.11
37461	BRD-A25234499	ASC	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.18	1.14
38311	BRD-A25234499	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38612	BRD-A25234499	PHH	10 uM	24 h	0.0	0.0	0.0	-0.41	-1.37	2.02
38835	BRD-A25234499	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91348	BRD-A25234499	HUH7	15 uM	72 h	0.21	0.87	0.01	0.41	1.45	2.22
119967	BRD-A25234499	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120014	BRD-A25234499	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.68
120082	BRD-A25234499	HT29	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120170	BRD-A25234499	PC3	1.11 uM	24 h	0.2	0.85	0.01	0.0	0.0	0.0
128788	BRD-A25234499	A375	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128823	BRD-A25234499	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128855	BRD-A25234499	YAPC	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary