CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00282
Pert ID:	BRD-K25114078
Compound Name:	aminoguanidine
Targets:	NOS2
MoA:	nitric oxide synthase inhibitor
SMILES:	NNC(N)=N
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
119929	BRD-K25114078	A375	0.04 uM	24 h	-0.31	-1.29	0.77	0.38	1.33	1.72
119963	BRD-K25114078	A549	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120011	BRD-K25114078	HA1E	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120078	BRD-K25114078	HT29	0.125 uM	24 h	0.0	0.0	0.0	0.3	1.06	0.59
120125	BRD-K25114078	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120202	BRD-K25114078	YAPC	1.11 uM	24 h	0.0	0.0	0.0	-0.23	-0.79	0.1
128822	BRD-K25114078	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.34	1.2	1.13
128839	BRD-K25114078	PC3	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary