CMap Candidate Details
Structure:
| CMap ID: | C02825 |
| Pert ID: | BRD-K22010301 |
| Compound Name: | JLK-6 |
| Targets: | PSEN1 |
| MoA: | gamma secretase inhibitor |
| SMILES: | COc1oc(=O)c2cc(N)ccc2c1Cl |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 2851 | BRD-K22010301 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3345 | BRD-K22010301 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.88 | 0.19 |
| 3475 | BRD-K22010301 | PC3 | 10 uM | 24 h | -0.22 | -0.92 | 0.06 | -0.35 | -1.18 | 1.15 |
| 3750 | BRD-K22010301 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39103 | BRD-K22010301 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39433 | BRD-K22010301 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39649 | BRD-K22010301 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39965 | BRD-K22010301 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40242 | BRD-K22010301 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.23 | 1.19 |
| 40599 | BRD-K22010301 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40771 | BRD-K22010301 | NEU | 10 uM | 24 h | 0.19 | 0.8 | 0.0 | 0.0 | 0.0 | 0.0 |
| 41072 | BRD-K22010301 | NPC | 10 uM | 24 h | 0.26 | 1.1 | 0.24 | -0.23 | -0.76 | 0.07 |
| 41403 | BRD-K22010301 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |